BDBM481856 5-[(7-methyl-6-oxo-purin-1- yl)methyl]-3-[(1R,3R)-3-(4- chlorophenyl)cyclopentyl]- 1,3,4-oxadiazol-2-one::US10913742, Example 100
SMILES Cn1cnc2ncn(Cc3nn([C@@H]4CC[C@H](C4)c4ccc(Cl)cc4)c(=O)o3)c(=O)c12
InChI Key InChIKey=INRPAICZXVSURJ-UKRRQHHQSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 481856
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Genentech
US Patent
Genentech
US Patent
Affinity DataIC50: 9.59nMAssay Description:The IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells express...More data for this Ligand-Target Pair