BDBM481861 3-[3-(4-chloro-3-fluoro- phenyl)cyclobutyl]-5-[(7- methyl-6-oxo-purin-1- yl)methyl]-1,3,4-oxadiazol- 2-one::US10913742, Example 106

SMILES Cn1cnc2ncn(Cc3nn([C@H]4C[C@@H](C4)c4ccc(Cl)c(F)c4)c(=O)o3)c(=O)c12

InChI Key InChIKey=XGTNKOQJOGMILW-HAQNSBGRSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 481861   

TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM481861(3-[3-(4-chloro-3-fluoro- phenyl)cyclobutyl]-5-[(7-...)
Affinity DataIC50:  29.9nMAssay Description:The IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells express...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent