BDBM482556 US10919852, Compound TABLE 1.255::US10919852, Compound TABLE 1.256::US11708326, Compound TABLE 1.256

SMILES Cc1c(OCCCN2CCC(C)(F)CC2)cccc1-c1cccc2[C@H](CCc12)Oc1cc(OCc2cncc(c2)C#N)c(CNC2CCC(=O)NC2)cc1Cl

InChI Key InChIKey=SLBQFKPSSNUWGE-JQKQRDFRSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 482556   

TargetProgrammed cell death protein 1(Homo sapiens)
Chemocentryx

US Patent
LigandPNGBDBM482556(US10919852, Compound TABLE 1.255 | US10919852, Com...)
Affinity DataIC50: <5nMAssay Description:96 Well plates were coated with 1 g/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in PBS (W...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProgrammed cell death 1 ligand 1(Homo sapiens (Human))
Chemocentryx

US Patent
LigandPNGBDBM482556(US10919852, Compound TABLE 1.255 | US10919852, Com...)
Affinity DataIC50:  253nMAssay Description:96 Well plates were coated with 1 μg/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProgrammed cell death 1 ligand 1(Homo sapiens (Human))
Chemocentryx

US Patent
LigandPNGBDBM482556(US10919852, Compound TABLE 1.255 | US10919852, Com...)
Affinity DataIC50: <5nMAssay Description:96 Well plates were coated with 1 μg/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProgrammed cell death protein 1(Homo sapiens)
Chemocentryx

US Patent
LigandPNGBDBM482556(US10919852, Compound TABLE 1.255 | US10919852, Com...)
Affinity DataIC50:  253nMAssay Description:96 Well plates were coated with 1 g/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in PBS (W...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent