BDBM483603 N-[(7S)-4-fluorobicyclo[4.2.0]octa-1,3,5- trien-7-yl]-N''-hydroxy-4-({cis-3-[(S- methylsulfonimidoyl)amino]cyclobutyl} oxy)-1,2,5-oxadiazole-3-carboximidamide (isomer 1)::US10927086, Example 61::US10927086, Example 62
SMILES CS(=N)(=O)N[C@H]1C[C@H](C1)Oc1nonc1\C(N[C@@H]1Cc2ccc(F)cc12)=N/O
InChI Key InChIKey=IBFPZVXJMRQATR-JLTZDMQQSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 483603
Affinity DataIC50: 146nMAssay Description:HIS-tagged IDO1 protein was recombinantly expressed in Escherichia coli using ZYP5052 autoinduction media supplemented with 500 μM delta aminole...More data for this Ligand-Target Pair
Affinity DataIC50: 81.6nMAssay Description:HIS-tagged IDO1 protein was recombinantly expressed in Escherichia coli using ZYP5052 autoinduction media supplemented with 500 μM delta aminole...More data for this Ligand-Target Pair