BDBM483765 1-((2R,4S)-2- methyl-4-(methyl(3- (trifluoromethyl)- benzyl)amino)- piperidine-1- carbonyl)-1H- pyrazole-3- carboxamide::US10927105, Ex 260::US11655217, Example 260

SMILES C[C@@H]1C[C@H](CCN1C(=O)n1ccc(n1)C(N)=O)N(C)Cc1cccc(c1)C(F)(F)F

InChI Key InChIKey=XEXPLYNXXWHDNW-CJNGLKHVSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 483765   

TargetMonoglyceride lipase(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM483765(1-((2R,4S)-2- methyl-4-(methyl(3- (trifluoromethyl...)
Affinity DataIC50: <100nMAssay Description:Proteomes (mouse brain membrane fraction for mouse assays; human prefrontal cortex membrane fractions for human assays) (50 mL, 1.0 mg/mL total prote...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoglyceride lipase(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM483765(1-((2R,4S)-2- methyl-4-(methyl(3- (trifluoromethyl...)
Affinity DataIC50: <100nMAssay Description:Proteomes (mouse brain membrane fraction for mouse assays; human prefrontal cortex membrane fractions for human assays) (50 mL, 1.0 mg/mL total prote...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent