BDBM484079 1-ethyl-8-fluoro-3-((R)- 3-((S)-2-hydroxy-3-(3- (isopropylsulfonyl) phenoxy)propylamino)- 1-oxa-8- azaspiro[4.5]decan-8- ylsulfonyl)quinolin- 4(1H)-one::US10927123, Compound 331

SMILES CCn1cc(c(=O)c2cccc(F)c12)S(=O)(=O)N1CCC2(C[C@H](CO2)NC[C@H](O)COc2cccc(c2)S(=O)(=O)C(C)C)CC1

InChI Key InChIKey=YCJFEWANNWEZDY-PKTZIBPZSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 484079   

TargetBeta-3 adrenergic receptor(Homo sapiens (Human))
Arena Pharmaceuticals

US Patent
LigandPNGBDBM484079(1-ethyl-8-fluoro-3-((R)- 3-((S)-2-hydroxy-3-(3- (i...)
Affinity DataIC50:  3.00E+4nMAssay Description:Compounds were dissolved and serially diluted (5-fold) in DMSO to generate a 10-point dose response stock. The stock was then diluted 100-fold in ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent