BDBM484199 (R,E)-2-(3-(1-(4-(2-Fluoro-3-methoxyphenoxy)phenyl)imidazo[1,5-a]pyrazin-3-yl)piperidine-1-carbonyl)-4,4-dimethylpent-2-enenitrile::US10933063, Compound 2::US11554118, Compound 2

SMILES COc1cccc(Oc2ccc(cc2)-c2nc([C@@H]3CCCN(C3)C(=O)C(=C\C(C)(C)C)\C#N)n3ccncc23)c1F

InChI Key InChIKey=YUUMOSQDRPMRPM-PLPWKKLYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 484199   

TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Suzhou Baijibugong Pharmaceutical Technology

US Patent
LigandPNGBDBM484199((R,E)-2-(3-(1-(4-(2-Fluoro-3-methoxyphenoxy)phenyl...)
Affinity DataIC50:  55nMAssay Description:Btk kinase activity was determined using a homogenous time resolved fluorescence (HTRF) methodology. Measurements were performed in a reaction volume...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticleUS Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Suzhou Baijibugong Pharmaceutical Technology

US Patent
LigandPNGBDBM484199((R,E)-2-(3-(1-(4-(2-Fluoro-3-methoxyphenoxy)phenyl...)
Affinity DataIC50:  55nMAssay Description:Btk and Other Kinases: Btk kinase activity was determined using a homogenous time resolved fluorescence (HTRF) methodology. Measurements were perform...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent