BDBM484461 US10934285, Example 47

SMILES CC1(N)CCN(CC1)c1nc2ccc(Sc3cccc(NC(=O)C4=C(O)CN(C4=O)c4ccccc4)c3Cl)nc2[nH]1

InChI Key InChIKey=QHQURGXEBKOABE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 484461   

TargetSH2B adapter protein 2(Human)
Novartis

US Patent
LigandPNGBDBM484461(US10934285, Example 47)
Affinity DataIC50:  3nMAssay Description:The inhibition of SHP2 by compounds of the invention (concentrations varying from 0.003-100 μM) was monitored using an assay in which 0.5 nM of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent