BDBM485593 N-((1S,3R)-3-Acrylamidocyclopentyl)-5-(*S)-(4-methyl-6- phenoxypyridin-3-yl)-4-oxo-4,5-dihydro-3H-1-thia-3,5,8- triazaacenaphthylene-2-carboxamide::US10934310, Ex # 430::US11319329, Ex # 430

SMILES Cc1cc(Oc2ccccc2)ncc1-n1c2ccnc3sc(C(=O)N[C@H]4CC[C@H](C4)NC(=O)C=C)c([nH]c1=O)c23

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 485593   

TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM485593(N-((1S,3R)-3-Acrylamidocyclopentyl)-5-(*S)-(4-meth...)
Affinity DataIC50:  6.76nMAssay Description:A BTK kinase lanthascreen binding assay monitors compound binding to unphosphorylated-BTK kinase domain (UP-BTK), by competing with a fluorescent lab...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM485593(N-((1S,3R)-3-Acrylamidocyclopentyl)-5-(*S)-(4-meth...)
Affinity DataIC50:  6.76nMAssay Description:A BTK kinase lanthascreen binding assay monitors compound binding to unphosphorylated-BTK kinase domain (UP-BTK), by competing with a fluorescent lab...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent