BDBM486622 US10947252, Example 58::US11427601, Example 58

SMILES CCn1nnc2c(C)c(ccc12)C(c1cnc(C)c(CN2CC3(CCOCC3)Oc3ncccc3S2(=O)=O)c1)C(C)(C)C(O)=O

InChI Key InChIKey=QXGZEGRFLMINNB-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 486622   

TargetKelch-like ECH-associated protein 1/Nuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM486622(US10947252, Example 58 | US11427601, Example 58)
Affinity DataKd:  2.40nMAssay Description:The ThermoFluorŪ is a fluorescence based assay (Tf) that estimates ligand binding affinities by measuring the effect of a ligand on protein thermal s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent