BDBM4867 CGP79787 Analog 50::CHEMBL75077::N-(4-chlorophenyl)-8-(pyridin-4-ylmethyl)pyrido[2,3-d]pyridazin-5-amine

SMILES Clc1ccc(Nc2nnc(Cc3ccncc3)c3ncccc23)cc1

InChI Key InChIKey=CZKWSFFVLCDVHL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 4867   

TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Novartis Pharmaceuticals

LigandPNGBDBM4867(CGP79787 Analog 50 | CHEMBL75077 | N-(4-chlorophen...)
Affinity DataIC50:  240nMpH: 7.5 T: 2°CAssay Description:The in vitro kinase assays were performed in 96-well plates using the recombinant GST-fused kinase domains expressed in baculovirus and purified over...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM4867(CGP79787 Analog 50 | CHEMBL75077 | N-(4-chlorophen...)
Affinity DataIC50:  240nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM4867(CGP79787 Analog 50 | CHEMBL75077 | N-(4-chlorophen...)
Affinity DataIC50:  130nMAssay Description:The in vitro kinase assays were performed in 96-well plates using the recombinant GST-fused kinase domains expressed in baculovirus and purified over...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed