BDBM487581 N-(5-chloro-6-(2H-1,2,3-triazol- 2-yl)pyridin-3-yl)-1-(naphthalen- 1-yl)-5-(trifluoromethyl)-1H- pyrazole-4-carboxamide::US10954214, Compound 2

SMILES FC(F)(F)c1c(cnn1-c1cccc2ccccc12)C(=O)Nc1cnc(c(Cl)c1)-n1nccn1

InChI Key InChIKey=NLXGPLTWMXADNH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 487581   

TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM487581(N-(5-chloro-6-(2H-1,2,3-triazol- 2-yl)pyridin-3-yl...)
Affinity DataIC50:  12nMAssay Description:MALT1 protease activity was assessed in an in vitro assay using a tetrapeptide as substrate and full-length MALT1 protein (Strep-MALT1(1-824)-His) pu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent