BDBM487587 N-(5-chloro-6-(2H-1,2,3-triazol- 2-yl)pyridin-3-yl)-1-(quinolin-5- yl)-5-(trifluoromethyl)-1H- pyrazole-4-carboxamide::US10954214, Compound 131::US10954214, Compound 8

SMILES FC(F)(F)c1c(cnn1-c1cccc2ncccc12)C(=O)Nc1cnc(c(Cl)c1)-n1nccn1

InChI Key InChIKey=PIMSRJDTTZEAIZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 487587   

TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM487587(N-(5-chloro-6-(2H-1,2,3-triazol- 2-yl)pyridin-3-yl...)
Affinity DataIC50:  17nMAssay Description:MALT1 protease activity was assessed in an in vitro assay using a tetrapeptide as substrate and full-length MALT1 protein (Strep-MALT1(1-824)-His) pu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM487587(N-(5-chloro-6-(2H-1,2,3-triazol- 2-yl)pyridin-3-yl...)
Affinity DataIC50:  13nMAssay Description:MALT1 protease activity was assessed in an in vitro assay using a tetrapeptide as substrate and full-length MALT1 protein (Strep-MALT1(1-824)-His) pu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent