BDBM487703 N-(5-chloro-6-(4-methyl-2H- 1,2,3-triazol-2-yl)pyridin-3-yl)- 1-(quinolin-5-yl)-5- (trifluoromethyl)-1H-pyrazole-4- carboxamide::US10954214, Compound 125

SMILES Cc1cnn(n1)-c1ncc(NC(=O)c2cnn(c2C(F)(F)F)-c2cccc3ncccc23)cc1Cl

InChI Key InChIKey=GCOMSHVHNYXRJM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 487703   

TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM487703(N-(5-chloro-6-(4-methyl-2H- 1,2,3-triazol-2-yl)pyr...)
Affinity DataIC50:  13nMAssay Description:MALT1 protease activity was assessed in an in vitro assay using a tetrapeptide as substrate and full-length MALT1 protein (Strep-MALT1(1-824)-His) pu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent