BDBM488058 N-(4-(4-(2- Methoxyethyl)piperazin- 1-yl)phenyl)-4-(3- (pyridin-3-yl)-1- (tetrahydrofuran-3- yl)-1H-pyrazol-4- yl)pyrimidin-2-amine::US10954216, Example 76

SMILES COCCN1CCN(CC1)c1ccc(Nc2nccc(n2)-c2cn(nc2-c2cccnc2)C2CCOC2)cc1

InChI Key InChIKey=GTNJYNMCDQMQRO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 488058   

TargetActivin receptor type-1 [R206H](Homo sapiens (Human))
Riken

US Patent
LigandPNGBDBM488058(N-(4-(4-(2- Methoxyethyl)piperazin- 1-yl)phenyl)-4...)
Affinity DataIC50:  1.30nMAssay Description:R206H: An overview of evaluation of an inhibitory effect of a compound of the present invention with respect to ALK2 (R206H) is as follows.In a buffe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent