BDBM488469 3-(3-Chloro-6-oxazol-2-yl-1H-indol-2-yl)-1- isopropyl-pyrazolo[3,4-d]pyrimidin-4-amine::US10954241, Example 109::US11548896, Example 109
SMILES CC(C)n1nc(-c2[nH]c3cc(ccc3c2Cl)-c2ncco2)c2c(N)ncnc12
InChI Key InChIKey=NSZXLMVQBNISCL-UHFFFAOYSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 488469
Affinity DataIC50: 6.29nMAssay Description:Kinase activity was detected using CisBio HTRF kinEASE kit based on time-resolved fluorescence transfer (FRET). The assay was performed in 384-well w...More data for this Ligand-Target Pair
Affinity DataIC50: 894nMAssay Description:Kinase activity was detected using CisBio HTRF kinEASE kit based on time-resolved fluorescence transfer (FRET). The assay was performed in 384-well w...More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase receptor Ret [V804M](Human)
Cancer Research Technology
US Patent
Cancer Research Technology
US Patent
Affinity DataIC50: 47.3nMAssay Description:RET, RETV804M and KDR: Kinase activity was detected using CisBio HTRF kinEASE kit based on time-resolved fluorescence transfer (FRET). The assay was ...More data for this Ligand-Target Pair
Affinity DataIC50: 6.29nMAssay Description:RET, RETV804M and KDR: Kinase activity was detected using CisBio HTRF kinEASE kit based on time-resolved fluorescence transfer (FRET). The assay was ...More data for this Ligand-Target Pair
Affinity DataIC50: 894nMAssay Description:RET, RETV804M and KDR: Kinase activity was detected using CisBio HTRF kinEASE kit based on time-resolved fluorescence transfer (FRET). The assay was ...More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase receptor Ret [V804M](Human)
Cancer Research Technology
US Patent
Cancer Research Technology
US Patent
Affinity DataIC50: 47.3nMAssay Description:Kinase activity was detected using CisBio HTRF kinEASE kit based on time-resolved fluorescence transfer (FRET). The assay was performed in 384-well w...More data for this Ligand-Target Pair