BDBM488641 US10961233, Example 19::US10961233, Example 22

SMILES Nc1nc(co1)C(=O)Nc1cc(ccc1Cl)N1CCN(CC1)C(=O)OCC1CNC1

InChI Key InChIKey=AFWQBYXPCSKICL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 488641   

LigandPNGBDBM488641(US10961233, Example 19 | US10961233, Example 22)
Affinity DataIC50: >100nMAssay Description:5 μl WT full length PAICS (final assay concentration, fac, 2.5 nM) in basic buffer, added to black, non-binding, 384-well plates (Corning #3575)...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM488641(US10961233, Example 19 | US10961233, Example 22)
Affinity DataIC50: >100nMAssay Description:5 μl WT full length PAICS (final assay concentration, fac, 2.5 nM) in basic buffer, added to black, non-binding, 384-well plates (Corning #3575)...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent