BDBM489301 Example 2-5::US10961242, Compound 16::US11548883, Compound 16

SMILES O=C(CCc1ccc2[nH]c(=O)oc2c1)N1CCC(CC1)c1cnc(NC2Cc3ccccc3C2)nc1

InChI Key InChIKey=DEXFNLNNUZKHNO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 489301   

TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Legochem Biosciences

US Patent
LigandPNGBDBM489301(Example 2-5 | US10961242, Compound 16 | US11548883...)
Affinity DataIC50:  2.20nMAssay Description:Two-fold dilution of each test compound solution (10 μM, 100% dimethyl sulfoxide) is carried out on 96-well V bottom plate (Costar 3363). After ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Legochem Biosciences

US Patent
LigandPNGBDBM489301(Example 2-5 | US10961242, Compound 16 | US11548883...)
Affinity DataIC50:  2.20nMAssay Description:Two-fold dilution of each test compound solution (10 μM, 100% dimethyl sulfoxide) is carried out on 96-well V bottom plate (Costar 3363). After ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent