BDBM490036 (S)-N-(1-((4-(N-(tert- butyl)sulfamoyl)phenyl)amino)-3- cyclohexyl-1-oxopropan-2- yl)cyclohexanecarboxamide::US10968172, ID # 14b

SMILES CC(C)(C)NS(=O)(=O)c1ccc(NC(=O)[C@H](CC2CCCCC2)NC(=O)C2CCCCC2)cc1

InChI Key InChIKey=KCQVOODGJSTOAU-QHCPKHFHSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 490036   

TargetUbiquitin carboxyl-terminal hydrolase 30(Homo sapiens (Human))
Mitobridge, Inc. (An Astellas)

Curated by ChEMBL
LigandPNGBDBM490036((S)-N-(1-((4-(N-(tert- butyl)sulfamoyl)phenyl)amin...)
Affinity DataIC50:  80nMAssay Description:Inhibition of USP30 (unknown origin) using Ubiquitin-Rhodamine110-Glycine as substrate incubated for 15 mins followed by substrate addition and measu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetUbiquitin carboxyl-terminal hydrolase 30(Homo sapiens (Human))
Mitobridge, Inc. (An Astellas)

Curated by ChEMBL
LigandPNGBDBM490036((S)-N-(1-((4-(N-(tert- butyl)sulfamoyl)phenyl)amin...)
Affinity DataIC50:  83nMAssay Description:The in vitro assay for USP30 evaluates the ability of a test compound to inhibit the activity of the enzyme to cleave ubiquitin from a substrate. Ubi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent