BDBM49021 (1-benzylbenzimidazol-2-yl)-(2-furfuryl)amine::1-benzyl-N-(furan-2-ylmethyl)benzimidazol-2-amine::MLS000084083::N-(2-furanylmethyl)-1-(phenylmethyl)-2-benzimidazolamine::N-(furan-2-ylmethyl)-1-(phenylmethyl)benzimidazol-2-amine::SMR000048469::cid_667146

SMILES C(Nc1nc2ccccc2n1Cc1ccccc1)c1ccco1

InChI Key InChIKey=OECUWHDVQIITIS-UHFFFAOYSA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 49021   

TargetD(1A) dopamine receptor(Homo sapiens (Human))
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM49021((1-benzylbenzimidazol-2-yl)-(2-furfuryl)amine | 1-...)
Affinity DataEC50:  0.00350nMAssay Description:Assay Provider: Val Watts Assay Provider Affiliation: Purdue University Grant Title: Allosteric Modulators of D1 Receptors Grant Number: 1 X01 MH0776...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetShort transient receptor potential channel 4(Homo sapiens)
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM49021((1-benzylbenzimidazol-2-yl)-(2-furfuryl)amine | 1-...)
Affinity DataIC50:  7.72E+4nMAssay Description:Inhibition of human TRPC4 channel expressed in HEK293 cells assessed as inhibition of EA-evoked Calcium influx by measuring reduction in intracellula...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetShort transient receptor potential channel 5(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM49021((1-benzylbenzimidazol-2-yl)-(2-furfuryl)amine | 1-...)
Affinity DataIC50:  6.50E+4nMAssay Description:Inhibition of human TRPC5 channel expressed in HEK293 cells assessed as inhibition of EA-evoked Calcium influx by measuring reduction in intracellula...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetShort transient receptor potential channel 5(Mus musculus)
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM49021((1-benzylbenzimidazol-2-yl)-(2-furfuryl)amine | 1-...)
Affinity DataIC50:  4.06E+3nMAssay Description:Inhibition of mouse TRPC5 expressed in Flp-In-T-Rex-HEK293 cells assessed as reduction in rulizole-induced channel current by automated patch clamp m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed