BDBM492379 US10975080, Example 77
SMILES CNc1nccc(-c2n[nH]c3nc(N4CCC5(C[C@@H](C)C[C@H]5N)CC4)n(C)c(=O)c23)c1Cl
InChI Key
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 492379
Affinity DataIC50: 30nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phosphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair