BDBM492963 5-((2-((tert-butyl(methyl)amino)meth-yl)benzyl)amino)-3-fluoro-6-methyl-N-(thiazol-4-yl)pyridine-2-sulfonamide::US10981905, Example 34

SMILES Cc1nc(c(F)cc1NCc1ccccc1CNCC(C)(C)C)S(=O)(=O)Nc1cscn1

InChI Key InChIKey=UIXFPTUAHLGYFW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 492963   

TargetSodium channel protein type 8 subunit alpha(Homo sapiens (Human))
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM492963(5-((2-((tert-butyl(methyl)amino)meth-yl)benzyl)ami...)
Affinity DataIC50:  37nMAssay Description:This sodium influx assay employs the use of the cell permeable, sodium sensitive dye ANG2 to quantify sodium ion influx through sodium channels which...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 1 subunit alpha(Homo sapiens (Human))
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM492963(5-((2-((tert-butyl(methyl)amino)meth-yl)benzyl)ami...)
Affinity DataIC50:  3.00E+4nMAssay Description:This sodium influx assay employs the use of the cell permeable, sodium sensitive dye ANG2 to quantify sodium ion influx through sodium channels which...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM492963(5-((2-((tert-butyl(methyl)amino)meth-yl)benzyl)ami...)
Affinity DataIC50:  3.00E+4nMAssay Description:This sodium influx assay employs the use of the cell permeable, sodium sensitive dye ANG2 to quantify sodium ion influx through sodium channels which...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent