BDBM495214 1-(3-Chloro-2-fluorobenzyl)-4-(5-(trans-2,6-dimethylmorpholino)-1H-pyrrolo[2,3-b]pyridin-3-yl)pyridin-2(1H)-one::US10995089, Example 112::US11708364, Example 112

SMILES C[C@H]1CN(C[C@H](C)O1)c1cnc2[nH]cc(-c3ccn(Cc4cccc(Cl)c4F)c(=O)c3)c2c1

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 495214   

TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Agv Discovery

US Patent
LigandPNGBDBM495214(1-(3-Chloro-2-fluorobenzyl)-4-(5-(trans-2,6-dimeth...)
Affinity DataIC50: <10nMAssay Description:To assess compounds capacity to inhibit ERK2 enzymatic activity, Z′-Lyte biochemical assay from Life technologies was used according to manufac...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Agv Discovery

US Patent
LigandPNGBDBM495214(1-(3-Chloro-2-fluorobenzyl)-4-(5-(trans-2,6-dimeth...)
Affinity DataIC50: <150nMAssay Description:To assess compounds capacity to inhibit ERK2 enzymatic activity, Z′-Lyte biochemical assay from Life technologies was used according to manufac...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent