BDBM495290 CVD-0018692::MAT-POS-e194df51-1

SMILES Clc1ccc2CN(C[C@@H](C(=O)Nc3cncc4ccccc34)c2c1)S(=O)(=O)CC1(CC1)C#N

InChI Key InChIKey=YAYDSAMHSQCKIM-OAQYLSRUSA-N

Data  2 IC50

PDB links: 2 PDB IDs match this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 495290   

TargetReplicase polyprotein 1ab(2019-nCoV)
Cornell University

LigandPNGBDBM495290(CVD-0018692 | MAT-POS-e194df51-1)
Affinity DataIC50:  37nMAssay Description:Compounds were seeded into assay-ready plates (Greiner 384 low volume, cat. no. 784900) using an Echo 555 acoustic dispenser, and dimethyl sulfoxide ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetReplicase polyprotein 1ab(2019-nCoV)
Cornell University

LigandPNGBDBM495290(CVD-0018692 | MAT-POS-e194df51-1)
Affinity DataIC50:  37nMAssay Description:Compounds were seeded into assay-ready plates (Greiner 384 low volume, cat 784900) using an Echo 555 acoustic dispenser, and DMSO was back-filled for...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails PDB3D3D Structure (crystal)