BDBM495402 CVD-0016452::EDJ-MED-611d11e7-4::PET-UNK-bcc8fd08-2

SMILES CO[C@]1(CCOc2ccc(Cl)cc12)C(=O)Nc1cncc2ccc(F)cc12

InChI Key InChIKey=PAPXBUNGDDTTOJ-FQEVSTJZSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 495402   

TargetReplicase polyprotein 1ab(2019-nCoV)
Israel Institution of Biological Research

LigandPNGBDBM495402(CVD-0016452 | EDJ-MED-611d11e7-4 | PET-UNK-bcc8fd0...)
Affinity DataIC50:  97nMAssay Description:Compounds were seeded into assay-ready plates (Greiner 384 low volume, cat 784900) using an Echo 555 acoustic dispenser, and DMSO was back-filled for...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails PDB3D3D Structure (crystal)
TargetReplicase polyprotein 1ab(2019-nCoV)
Israel Institution of Biological Research

LigandPNGBDBM495402(CVD-0016452 | EDJ-MED-611d11e7-4 | PET-UNK-bcc8fd0...)
Affinity DataIC50:  164nMAssay Description:Compounds were seeded into assay-ready plates (Greiner 384 low volume, cat. no. 784900) using an Echo 555 acoustic dispenser, and dimethyl sulfoxide ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetReplicase polyprotein 1ab(2019-nCoV)
Israel Institution of Biological Research

LigandPNGBDBM495402(CVD-0016452 | EDJ-MED-611d11e7-4 | PET-UNK-bcc8fd0...)
Affinity DataIC50:  97nMAssay Description:Compounds were seeded into assay-ready plates (Greiner 384 low volume, cat 784900) using an Echo 555 acoustic dispenser, and DMSO was back-filled for...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails PDB3D3D Structure (crystal)