BDBM50001683 13-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7-benzyl-3,3,14,14-tetramethyl-6,9,12-trioxo-1,2-dithia-5,8,11-triaza-cyclotetradecane-4-carboxylic acid::7-Benzyl-10-{[3-(4-hydroxy-phenyl)-pyrrolidine-2-carbonyl]-amino}-3,3-dimethyl-6,9-dioxo-1,2-dithia-5,8-diaza-cycloundecane-4-carboxylic acid::CHEMBL294616::DPDPE

SMILES CC1(C)SSC(C)(C)[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)NCC(=O)N[C@H](Cc2ccccc2)C(=O)N[C@H]1C(O)=O

InChI Key InChIKey=MCMMCRYPQBNCPH-UHFFFAOYSA-N

Data  46 KI  76 IC50  2 Kd  20 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 144 hits for monomerid = 50001683   

TargetDelta-type opioid receptor(Mouse)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50001683(CHEMBL294616 | 13-[2-Amino-3-(4-hydroxy-phenyl)-pr...)
Affinity DataIC50: 4.10nMAssay Description:Compound was evaluated for its inhibitory potency against opioid receptor delta of Mouse vas deferensMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50001683(CHEMBL294616 | 13-[2-Amino-3-(4-hydroxy-phenyl)-pr...)
Affinity DataIC50: 1.60nMAssay Description:Compound was evaluated for the binding affinity in comparison with [3H][p-Cl-Phe4]-DPDPE (delta opioid receptor selective ligand)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50001683(CHEMBL294616 | 13-[2-Amino-3-(4-hydroxy-phenyl)-pr...)
Affinity DataIC50: 7.30E+3nMAssay Description:Compound was evaluated for its inhibitory potency against opioid receptor delta of Guinea pig ileumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50001683(CHEMBL294616 | 13-[2-Amino-3-(4-hydroxy-phenyl)-pr...)
Affinity DataIC50: 609nMAssay Description:Compound was evaluated for its ability to displace [3H]- CTOP (opioid receptor mu selective ligand)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50001683(CHEMBL294616 | 13-[2-Amino-3-(4-hydroxy-phenyl)-pr...)
Affinity DataKd:  577nMAssay Description:Binding affinity against Mu opioid receptor using [35S]GTP-gamma-S, binding assay in guinea pig caudate membranes in unblocked conditionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50001683(CHEMBL294616 | 13-[2-Amino-3-(4-hydroxy-phenyl)-pr...)
Affinity DataKd:  577nMAssay Description:Binding affinity against Mu opioid receptor using [35S]GTP-gamma-S, binding assay in guinea pig caudate membranes blocked with 6000 nM CTAPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50001683(CHEMBL294616 | 13-[2-Amino-3-(4-hydroxy-phenyl)-pr...)
Affinity DataIC50: 4nMAssay Description:Binding affinity against rat Opioid receptor delta 1 expressed in CHO cells determined by competitive inhibition of 1 nM [3H]DPDPE.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50001683(CHEMBL294616 | 13-[2-Amino-3-(4-hydroxy-phenyl)-pr...)
Affinity DataIC50: 5.50E+3nMAssay Description:Compound is tested in vitro in guinea pig ileum (GPI) assay mediated by Opioid receptor mu 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50001683(CHEMBL294616 | 13-[2-Amino-3-(4-hydroxy-phenyl)-pr...)
Affinity DataIC50: 1.30E+3nMAssay Description:Opioid receptor mu 1 binding affinity in rat brain membrane preparations by the displacement of [3H]- DAGOMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50001683(CHEMBL294616 | 13-[2-Amino-3-(4-hydroxy-phenyl)-pr...)
Affinity DataIC50: 2.70nMAssay Description:Compound is tested in vitro in mouse vas deferens (MVD) assay mediated by Opioid receptor delta 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50001683(CHEMBL294616 | 13-[2-Amino-3-(4-hydroxy-phenyl)-pr...)
Affinity DataIC50: 5.80nMAssay Description:Opioid receptor binding affinity in rat brain membrane preparations by the displacement of [3H]DSLET (Opioid receptor delta 1-selective radioligand)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50001683(CHEMBL294616 | 13-[2-Amino-3-(4-hydroxy-phenyl)-pr...)
Affinity DataIC50: 4.10nMAssay Description:Inhibitory activity measured against Opioid receptor delta 1 using mouse vas deference assay (MVD).More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50001683(CHEMBL294616 | 13-[2-Amino-3-(4-hydroxy-phenyl)-pr...)
Affinity DataIC50: 7.30E+3nMAssay Description:Inhibitory activity measured against Opioid receptor mu 1 using guinea pig ileum assay (GPI).More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50001683(CHEMBL294616 | 13-[2-Amino-3-(4-hydroxy-phenyl)-pr...)
Affinity DataIC50: 619nMAssay Description:Inhibitory activity measured against [3H]CTOP (Opioid receptor mu 1) in rat brain using radioreceptor binding assays.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50001683(CHEMBL294616 | 13-[2-Amino-3-(4-hydroxy-phenyl)-pr...)
Affinity DataIC50: 5.80nMAssay Description:Inhibitory activity measured against [3H]DPDPE (Opioid receptor delta 1 ligand) in rat brain using radioreceptor binding assays.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50001683(CHEMBL294616 | 13-[2-Amino-3-(4-hydroxy-phenyl)-pr...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of electrically evoked contraction of guinea pig ileum (myenteric plexus:longitudinal muscle preparation) by antagonist action at mu 1 opi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50001683(CHEMBL294616 | 13-[2-Amino-3-(4-hydroxy-phenyl)-pr...)
Affinity DataIC50: 385nMAssay Description:The ability to displace [3H]naloxone from the Opioid receptor mu 1 isolated from rat brain membrane.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50001683(CHEMBL294616 | 13-[2-Amino-3-(4-hydroxy-phenyl)-pr...)
Affinity DataIC50: 5.30nMAssay Description:Ability to displace [3H]DPDPE from Opioid receptor delta 1 in rat brain membranes, was determined from radioreceptor assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50001683(CHEMBL294616 | 13-[2-Amino-3-(4-hydroxy-phenyl)-pr...)
Affinity DataIC50: 609nMAssay Description:Ability to displace [3H]CTOP from Opioid receptor mu 1 in rat brain membranes, was determined from radioreceptor assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50001683(CHEMBL294616 | 13-[2-Amino-3-(4-hydroxy-phenyl)-pr...)
Affinity DataIC50: 7.30E+3nMAssay Description:Tested for agonist activity against mu opioid receptor in guinea pig ileumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50001683(CHEMBL294616 | 13-[2-Amino-3-(4-hydroxy-phenyl)-pr...)
Affinity DataIC50: 5.10nMAssay Description:Tested for agonist activity against delta opioid receptor mouse vas deferensMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50001683(CHEMBL294616 | 13-[2-Amino-3-(4-hydroxy-phenyl)-pr...)
Affinity DataIC50: 7.30E+3nMAssay Description:Binding affinity towards Opioid receptor mu 1 was determined in guinea pig whole brain using [3H]CTOP radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50001683(CHEMBL294616 | 13-[2-Amino-3-(4-hydroxy-phenyl)-pr...)
Affinity DataIC50: 4.10nMAssay Description:Binding affinity towards Opioid receptor delta 1 was determined in guinea pig whole brain using [3H][4''-Cl-Phe4]-DPDPE as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50001683(CHEMBL294616 | 13-[2-Amino-3-(4-hydroxy-phenyl)-pr...)
Affinity DataIC50: 1.80nMAssay Description:Inhibitory concentration was determined against delta-opioid receptor using [3H]- DPDPE radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50001683(CHEMBL294616 | 13-[2-Amino-3-(4-hydroxy-phenyl)-pr...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory concentration against Opioid receptor kappa 1 using [3H]- U-69,593 radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50001683(CHEMBL294616 | 13-[2-Amino-3-(4-hydroxy-phenyl)-pr...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory concentration was determined against Opioid receptor mu 1 using [3H]- DAMGO radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50001683(CHEMBL294616 | 13-[2-Amino-3-(4-hydroxy-phenyl)-pr...)
Affinity DataIC50: 1.80nMAssay Description:Tested for inhibitory concentration against [3H]DPDPE binding at sites of delta-opioid receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50001683(CHEMBL294616 | 13-[2-Amino-3-(4-hydroxy-phenyl)-pr...)
Affinity DataIC50: 1.00E+3nMAssay Description:Tested for inhibitory concentration against [3H]U-69593 binding at sites of kappa-opioid receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50001683(CHEMBL294616 | 13-[2-Amino-3-(4-hydroxy-phenyl)-pr...)
Affinity DataIC50: 1.00E+3nMAssay Description:Tested for inhibitory concentration against [3H]DAMGO binding at sites of mu-opioid receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50001683(CHEMBL294616 | 13-[2-Amino-3-(4-hydroxy-phenyl)-pr...)
Affinity DataIC50: 4.10nMAssay Description:Opioid activity against delta-receptor of isolated mouse vas deferens(MVD) at 30 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50001683(CHEMBL294616 | 13-[2-Amino-3-(4-hydroxy-phenyl)-pr...)
Affinity DataIC50: 7.30E+3nMAssay Description:The opioid activity against the mu-receptor in the isolated guinea pig ileum(GPI)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50001683(CHEMBL294616 | 13-[2-Amino-3-(4-hydroxy-phenyl)-pr...)
Affinity DataIC50: 7.30E+3nMAssay Description:Agonistic activity for Opioid receptor mu 1 as inhibitory activity towards electrically stimulated guinea pig ileumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50001683(CHEMBL294616 | 13-[2-Amino-3-(4-hydroxy-phenyl)-pr...)
Affinity DataIC50: 4.10nMAssay Description:Agonistic activity towards Opioid receptor delta 1 as inhibitory activity towards electrically stimulated mouse vas deferensMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50001683(CHEMBL294616 | 13-[2-Amino-3-(4-hydroxy-phenyl)-pr...)
Affinity DataIC50: 1.76E+3nMAssay Description:Tested for the binding affinity against the Mu opioid receptor in guinea pig brain using [3H]-DAMGOMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50001683(CHEMBL294616 | 13-[2-Amino-3-(4-hydroxy-phenyl)-pr...)
Affinity DataIC50: 5.00E+3nMAssay Description:Tested for the binding affinity against the Delta opioid receptor in guinea pig brain using [3H]DPDPEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50001683(CHEMBL294616 | 13-[2-Amino-3-(4-hydroxy-phenyl)-pr...)
Affinity DataIC50: 2.10nMAssay Description:Tested for the binding affinity against the Kappa opioid receptor in guinea pig brain using [3H]U-69593More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50001683(CHEMBL294616 | 13-[2-Amino-3-(4-hydroxy-phenyl)-pr...)
Affinity DataIC50: 7.30E+3nMAssay Description:Inhibitory activity of the electrically induced guinea pig ileum longitudinal muscle-myenteric plexusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50001683(CHEMBL294616 | 13-[2-Amino-3-(4-hydroxy-phenyl)-pr...)
Affinity DataEC50:  7.30E+3nMAssay Description:Effective concentration was measured towards mu opioid receptor using guinea pig ileum (GPI, mu) bioassay in vitroMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50001683(CHEMBL294616 | 13-[2-Amino-3-(4-hydroxy-phenyl)-pr...)
Affinity DataIC50: 609nMAssay Description:Binding affinity opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50001683(CHEMBL294616 | 13-[2-Amino-3-(4-hydroxy-phenyl)-pr...)
Affinity DataIC50: 1.60nMAssay Description:Binding affinity opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50001683(CHEMBL294616 | 13-[2-Amino-3-(4-hydroxy-phenyl)-pr...)
Affinity DataEC50:  4.10nMAssay Description:Effective concentration was measured towards delta opioid receptor using mouse vas deferens(MVD, delta) bioassay in vitroMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Mouse)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50001683(CHEMBL294616 | 13-[2-Amino-3-(4-hydroxy-phenyl)-pr...)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibitory potency against Opioid receptor mu 1 was determined in electrically induced strips of guinea pig ileum (GPI)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50001683(CHEMBL294616 | 13-[2-Amino-3-(4-hydroxy-phenyl)-pr...)
Affinity DataIC50: 10nMAssay Description:Inhibition of binding of radioligand [3H][p-Cl-phe]-DPDPE to Opioid receptor delta 1 in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50001683(CHEMBL294616 | 13-[2-Amino-3-(4-hydroxy-phenyl)-pr...)
Affinity DataIC50: 2.5nMAssay Description:Inhibitory potency against Opioid receptor delta 1 was determined in electrically induced smooth muscle contractions of mouse vas deferens (MVD)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50001683(CHEMBL294616 | 13-[2-Amino-3-(4-hydroxy-phenyl)-pr...)
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of binding of radioligand [3H]CTOP to Opioid receptor mu 1 in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50001683(CHEMBL294616 | 13-[2-Amino-3-(4-hydroxy-phenyl)-pr...)
Affinity DataIC50: 609nMAssay Description:Binding affinity was measured against Opioid receptor mu 1 using [3H]-DAMGO as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50001683(CHEMBL294616 | 13-[2-Amino-3-(4-hydroxy-phenyl)-pr...)
Affinity DataIC50: 1.60nMAssay Description:Binding affinity was measured against Opioid receptor delta 1 using [3H]p-Cl-DPDPE as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50001683(CHEMBL294616 | 13-[2-Amino-3-(4-hydroxy-phenyl)-pr...)
Affinity DataIC50: 5.10nMAssay Description:Agonist activity was evaluated in guinea pig ileum (GPI) preparations at Opioid receptor delta 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50001683(CHEMBL294616 | 13-[2-Amino-3-(4-hydroxy-phenyl)-pr...)
Affinity DataIC50: 7.30E+3nMAssay Description:Agonist activity was evaluated in guinea pig ileum (GPI) preparations at Opioid receptor mu 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50001683(CHEMBL294616 | 13-[2-Amino-3-(4-hydroxy-phenyl)-pr...)
Affinity DataIC50: 620nMAssay Description:Binding affinity towards mu opioid receptor was determined in rat brain using [3H]CTOP as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2012
Entry Details Article
PubMed
Displayed 1 to 50 (of 144 total ) | Next | Last >>