BDBM50002861 3-(4,5-Diphenyl-oxazol-2-yl)-propionic acid::CHEMBL1071::Daypro::OXAPROZIN::WY-21743::oxaprosin

SMILES OC(=O)CCc1nc(c(o1)-c1ccccc1)-c1ccccc1

InChI Key InChIKey=OFPXSFXSNFPTHF-UHFFFAOYSA-N

Data  2 KI  24 IC50  2 Kd  3 EC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50002861   

TargetComplement C5(Homo sapiens)
Indian Institute Of Technology Bhubaneswar

Curated by ChEMBL
LigandPNGBDBM50002861(3-(4,5-Diphenyl-oxazol-2-yl)-propionic acid | CHEM...)
Affinity DataKd:  640nMAssay Description:Binding affinity to human C5a assessed as dissociation constant after 1 hr by circular dichroism analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1a(Human SARS coronavirus (SARS-CoV))
University Of Science And Technology Of China

Curated by ChEMBL
LigandPNGBDBM50002861(3-(4,5-Diphenyl-oxazol-2-yl)-propionic acid | CHEM...)
Affinity DataKd:  1.00E+6nMAssay Description:Binding affinity to 15N-labelled His6-tagged SARS-CoV Mac3 (527 to 652 residue) expressed in Escherichia coli Rosetta assessed as chemical shift pert...More data for this Ligand-Target Pair
In DepthDetails PubMed