BDBM50004822 (R)-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol::(R)-7,8-Dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepinium::1-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol::1-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol(SKF38393)::7,8-Dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepinium(R(+)SKF38393)::CHEMBL1467585::CHEMBL24077::R(+)SKF 383931-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol::SK&F-383933::SK-38393::SK-383933::SKF 38393::SKF 38393 (+)
SMILES Oc1cc2CCNC[C@H](c3ccccc3)c2cc1O
InChI Key InChIKey=JUDKOGFHZYMDMF-CQSZACIVSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 12 hits for monomerid = 50004822
Affinity DataEC50: 32nMAssay Description:Inhibition of Rap1A-mediated geranylgeranylation expressed in mouse NIH3T3 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human dopamine D2 receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP productionMore data for this Ligand-Target Pair
Affinity DataEC50: 30nMAssay Description:Agonist activity at human recombinant dopamine D1 receptor expressed in CHO cells assessed as stimulation of cAMP productionMore data for this Ligand-Target Pair
Affinity DataEC50: 59nMAssay Description:Adenylate cyclase assay carried out in LTK cells transfected with human Dopamine receptor D1More data for this Ligand-Target Pair
Affinity DataEC50: 950nMAssay Description:Ability to stimulate the Dopamine receptor D1 like was assayed by measuring cAMP production in cell free homogenates of goldfish retinal tissueMore data for this Ligand-Target Pair
TargetAdenylate cyclase type 5(Homo sapiens (Human))
Royal Danish School Of Pharmacy
Curated by ChEMBL
Royal Danish School Of Pharmacy
Curated by ChEMBL
Affinity DataEC50: 80nMAssay Description:Effective concentration required to stimulate Adenylate cyclaseMore data for this Ligand-Target Pair
Affinity DataEC50: 56nMAssay Description:Agonist activity at human dopamine D1 receptor expressed in HEK293 cells assessed as cAMP accumulation after 15 minsMore data for this Ligand-Target Pair
Affinity DataEC50: 100nMAssay Description:Tested for its affinity towards Dopamine receptor D1 in rat striatal membraneMore data for this Ligand-Target Pair
Affinity DataEC50: >5.00E+3nMAssay Description:Adenylate cyclase assay carried out in LTK cells transfected with human Dopamine receptor D2More data for this Ligand-Target Pair
Affinity DataEC50: 386nMAssay Description:Concentration required to inhibit 50% dopamine receptor D1 activity using cell free homogenate of carp retinaMore data for this Ligand-Target Pair
TargetAdenylate cyclase type 1/2/3/4/5/6/7/8/9(Homo sapiens (Human))
University Of Lund
Curated by ChEMBL
University Of Lund
Curated by ChEMBL
Affinity DataEC50: 71nMAssay Description:Compound was tested for the adenylate cyclase stimulationMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Dupont Pharmaceuticals
Curated by PDSP Ki Database
Dupont Pharmaceuticals
Curated by PDSP Ki Database
Affinity DataEC50: >1.00E+4nMAssay Description:Concentration required to inhibit 50% dopamine receptor D2 in a cell free homogenate of intermediate lobe of pituitary glandMore data for this Ligand-Target Pair