BDBM50004997 CHEMBL2392427

SMILES NS(=O)(=O)c1ccc(CCNCc2cccc3ccccc23)cc1

InChI Key InChIKey=VXZRQQMOCBAJCN-UHFFFAOYSA-N

Data  5 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50004997   

TargetCarbonic anhydrase 4(Homo sapiens (Human))
University Of Firenze

Curated by ChEMBL
LigandPNGBDBM50004997(CHEMBL2392427)
Affinity DataKi:  0.900nMAssay Description:Inhibition of recombinant human CA4 pre-incubated for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
University Of Firenze

Curated by ChEMBL
LigandPNGBDBM50004997(CHEMBL2392427)
Affinity DataKi:  45nMAssay Description:Inhibition of recombinant human CA9 pre-incubated for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCarbonic anhydrase 12(Homo sapiens (Human))
University Of Firenze

Curated by ChEMBL
LigandPNGBDBM50004997(CHEMBL2392427)
Affinity DataKi:  46nMAssay Description:Inhibition of recombinant human CA12 pre-incubated for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University Of Firenze

Curated by ChEMBL
LigandPNGBDBM50004997(CHEMBL2392427)
Affinity DataKi:  47nMAssay Description:Inhibition of recombinant human CA2 pre-incubated for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
University Of Firenze

Curated by ChEMBL
LigandPNGBDBM50004997(CHEMBL2392427)
Affinity DataKi:  82nMAssay Description:Inhibition of recombinant human CA1 pre-incubated for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University Of Firenze

Curated by ChEMBL
LigandPNGBDBM50004997(CHEMBL2392427)
Affinity DataIC50:  153nMAssay Description:Inhibition of full length carbonic anhydrase-2 in human erythrocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
University Of Firenze

Curated by ChEMBL
LigandPNGBDBM50004997(CHEMBL2392427)
Affinity DataIC50:  19nMAssay Description:Inhibition of GST-tagged recombinant carbonic anhydrase-9 catalytic domain (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
University Of Firenze

Curated by ChEMBL
LigandPNGBDBM50004997(CHEMBL2392427)
Affinity DataIC50:  173nMAssay Description:Inhibition of full length carbonic anhydrase-1 in human erythrocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed