BDBM50005751 CHEMBL3235844

SMILES Fc1ccc(CN2CCc3nc(ncc3C2)N2CCN(CC2)c2ncccn2)cc1

InChI Key InChIKey=KHQUUMKKXZTNQA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50005751   

TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50005751(CHEMBL3235844)
Affinity DataIC50: >1.00E+5nMAssay Description:Displacement of FITC-geldanamycin from HSP90 (unknown origin) after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50005751(CHEMBL3235844)
Affinity DataIC50:  4.02E+4nMAssay Description:Inhibition of full-length HSP90 (unknown origin) expressed in Escherichia coli assessed as inhibition of ATPase activity after 3 hrs by spectrophotom...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed