BDBM50006417 CHEMBL2367471::Sodium; 7-[1-benzothiazol-2-yl-5-(4-fluoro-phenyl)-3-isopropyl-1H-pyrazol-4-yl]-3,5-dihydroxy-hept-6-enoate

SMILES [Na+].CC(C)c1nn(-c2nc3ccccc3s2)c(c1\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)-c1ccc(F)cc1

InChI Key InChIKey=GBDPLSIGKZIIKF-NRFPMOEYSA-M

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50006417   

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50006417(CHEMBL2367471 | Sodium; 7-[1-benzothiazol-2-yl-5-(...)
Affinity DataIC50:  59nMAssay Description:Tested in vitro for the inhibition of HMG-CoA reductase from partially purified microsomal preparations.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed