BDBM50007728 CHEMBL424121::DB867
SMILES NC(=N)c1ccc(cc1)-c1ccc(o1)-c1ccc(nc1)C(N)=N
InChI Key InChIKey=IFAJVIYMOBCWOU-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50007728
TargetProtein arginine N-methyltransferase 1 [11-371](Homo sapiens (Human))
The University Of Georgia
Curated by ChEMBL
The University Of Georgia
Curated by ChEMBL
Affinity DataIC50: 7.20E+3nMAssay Description:Inhibition of His6x-tagged recombinant PRMT1 (unknown origin) expressed in Escherichia coli BL21(DE3) using [3H]SAM and histone H4 (1 to 20) as subst...More data for this Ligand-Target Pair
TargetProtein arginine N-methyltransferase 6(Homo sapiens (Human))
The University Of Georgia
Curated by ChEMBL
The University Of Georgia
Curated by ChEMBL
Affinity DataIC50: 2.11E+5nMAssay Description:Inhibition of His6x-tagged PRMT6 (unknown origin) using [3H]SAM and histone H3.1 as substrate at 20 uM after 1 hr by P81 filter binding assayMore data for this Ligand-Target Pair
TargetHistone-arginine methyltransferase CARM1(Homo sapiens (Human))
The University Of Georgia
Curated by ChEMBL
The University Of Georgia
Curated by ChEMBL
Affinity DataIC50: >4.00E+5nMAssay Description:Inhibition of GST-tagged CARM1 (unknown origin) using [3H]SAM and histone H3.1 as substrate at 20 uM after 1 hr by P81 filter binding assayMore data for this Ligand-Target Pair
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
The University Of Georgia
Curated by ChEMBL
The University Of Georgia
Curated by ChEMBL
Affinity DataIC50: 1.86E+5nMAssay Description:Inhibition of HA-tagged recombinant PRMT5 (unknown origin) expressed in HEK293T cells using [3H]SAM and histone H4 (1 to 20) as substrate after 8 min...More data for this Ligand-Target Pair