BDBM50008371 CHEMBL127385::H-Thi-Lys-AspMet-GIn-Leu-Gly-Arg-OH

SMILES CSCC[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](N)Cc1cccs1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(O)=O

InChI Key InChIKey=LCMYHRLGWJEHSA-NHPMDPCJSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50008371   

TargetC5a anaphylatoxin chemotactic receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50008371(CHEMBL127385 | H-Thi-Lys-AspMet-GIn-Leu-Gly-Arg-OH)
Affinity DataKi:  2.10E+3nMAssay Description:Inhibitory activity against [125I]-rC5a binding to C5a anaphylatoxin chemotactic receptor in human polymorphonuclear leukocyte (PMNL) membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMyeloperoxidase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50008371(CHEMBL127385 | H-Thi-Lys-AspMet-GIn-Leu-Gly-Arg-OH)
Affinity DataEC50:  2.00E+5nMAssay Description:In vivo potency of the compound was determined as the maximal lysosomal myeloperoxidase (MPO) release in PMNL assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed