BDBM50008990 1,2-Dihydro-indazol-3-one::1H-indazol-3-ol::CHEMBL276725

SMILES O=c1[nH][nH]c2ccccc12

InChI Key InChIKey=SWEICGMKXPNXNU-UHFFFAOYSA-N

Data  5 IC50  1 Kd  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50008990   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50008990(1,2-Dihydro-indazol-3-one | 1H-indazol-3-ol | CHEM...)
Affinity DataIC50:  2.00E+3nMAssay Description:In vitro inhibition of LTB4 production was measured in rat bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1/2(RAT)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50008990(1,2-Dihydro-indazol-3-one | 1H-indazol-3-ol | CHEM...)
Affinity DataIC50:  3.00E+4nMAssay Description:In vitro inhibition of PGE-2 production was measured in rat bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50008990(1,2-Dihydro-indazol-3-one | 1H-indazol-3-ol | CHEM...)
Affinity DataEC50: >7.45E+5nMAssay Description:Ex vivo inhibition of LTB4 production was measured in dog bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50008990(1,2-Dihydro-indazol-3-one | 1H-indazol-3-ol | CHEM...)
Affinity DataIC50:  700nMAssay Description:In vitro inhibition of LTB4 (LT) production in dog bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed