BDBM50010209 CHEMBL3251694::L-Isoseryl-L-leucine hydrochloride (12b)

SMILES CC(C)C[C@H](NC(=O)[C@@H](O)CN)C(O)=O

InChI Key InChIKey=BIYDZHKIVFQYDX-BQBZGAKWSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50010209   

TargetAminopeptidase N(Sus scrofa (Pig))
Shandong University

LigandPNGBDBM50010209(CHEMBL3251694 | L-Isoseryl-L-leucine hydrochloride...)
Affinity DataIC50:  1.99E+5nMAssay Description:The samples and positive controls were serial diluted to various concentrations: 1280 μg/mL, 320 μg/mL, 80 μg/mL, and 20 μg/mL, 5...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase B(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50010209(CHEMBL3251694 | L-Isoseryl-L-leucine hydrochloride...)
Affinity DataIC50:  6.40E+5nMAssay Description:Inhibition of rat liver aminopeptidase B using 0.2 mM L-leucine-beta-naphthylamide by colorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Shandong University

LigandPNGBDBM50010209(CHEMBL3251694 | L-Isoseryl-L-leucine hydrochloride...)
Affinity DataIC50:  3.64E+5nMpH: 8.5 T: 2°CAssay Description:The compound samples were assayed for inhibitory activity against MMP-2 in 96-well microplates using succinylated gelatin as the substrate. The compo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed