BDBM50012632 CHEMBL2333941

SMILES C[C@]1(CCSC(N)=N1)c1cc(c(F)cc1F)-c1cncnc1

InChI Key InChIKey=MJQMRGWYPNIERM-HNNXBMFYSA-N

Data  21 IC50  1 EC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50012632   

TargetBeta-secretase 1(Homo sapiens (Human))
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50012632(CHEMBL2333941)
Affinity DataEC50:  300nMAssay Description:Inhibition of BACE1 in HEK293 cells expressing APPswedish mutant assessed as inhibition of amyloid beta production by ELISAMore data for this Ligand-Target Pair