BDBM50014434 CHEMBL3261427
SMILES C[C@@H](CNc1cccc2n(ncc12)-c1ccc(cc1)C#N)NS(=O)(=O)c1c(C)nn(C2CCCC2)c1C
InChI Key InChIKey=MKMJTAAVJXMHJQ-SFHVURJKSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50014434
Affinity DataIC50: 16nMAssay Description:Agonist activity at glucocorticoid receptor in human Chago K1 cells assessed as gene transrepression by Lac-Z reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Agonist activity at glucocorticoid receptor in human PBMC assessed as inhibition of LPS-stimulated TNF-alpha releaseMore data for this Ligand-Target Pair
Affinity DataIC50: 4.70nMAssay Description:Binding affinity to human glucocorticoid receptor by fluorescence polarization assayMore data for this Ligand-Target Pair