BDBM50014757 (4-Chloro-phenyl)-(2-chloro-phenyl)-pyridin-3-yl-methanol : (Hydrochloride)::CHEMBL137192

SMILES OC(c1ccc(Cl)cc1)(c1cccnc1)c1ccccc1Cl

InChI Key InChIKey=AKDCDVNDPAZRSM-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50014757   

TargetCytochrome P450 3A4/3A5(Homo sapiens (Human))
Epichem

Curated by ChEMBL
LigandPNGBDBM50014757((4-Chloro-phenyl)-(2-chloro-phenyl)-pyridin-3-yl-m...)
Affinity DataIC50:  600nMAssay Description:Inhibition of CYP3A4/5 in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Rattus norvegicus)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50014757((4-Chloro-phenyl)-(2-chloro-phenyl)-pyridin-3-yl-m...)
Affinity DataEC50: >2.00E+3nMAssay Description:In vitro Cytochrome P450 19A1 inhibition concentration to decrease aromatization of androstenedione in rat ovarian microsomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed