BDBM50015454 CHEMBL3264995

SMILES COc1ccc(Nc2nc(cn3ccnc23)-c2cccc(c2)C(=O)Nc2ccc(cc2)C(O)=O)cc1OC

InChI Key InChIKey=VCLOZUGEZMWXFF-UHFFFAOYSA-N

Data  1 IC50  1 Kd  1 EC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50015454   

TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50015454(CHEMBL3264995)
Affinity DataEC50:  175nMAssay Description:Inhibition of Syk in antihuman IgM-stimulated human Ramos cells assessed as decrease in BCR-mediated BLNK phosphorylation by cellular assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50015454(CHEMBL3264995)
Affinity DataIC50:  0.840nMAssay Description:Inhibition of full length Syk (unknown origin) using biotinylated peptide substrateMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50015454(CHEMBL3264995)
Affinity DataKd:  4nMAssay Description:Binding affinity to Syk (unknown origin)More data for this Ligand-Target Pair