BDBM50015876 7-Acetoxy-3-acetoxymethyl-5,5,8-trioxo-5lambda*6*-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid tert-butyl ester::CHEMBL84768

SMILES CC(=O)OCC1=C(N2[C@@H]([C@@H](OC(C)=O)C2=O)S(=O)(=O)C1)C(=O)OC(C)(C)C

InChI Key InChIKey=BLNBFCPVEGNWAN-GXTWGEPZSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50015876   

TargetSerine protease 1(Bos taurus (bovine))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50015876(7-Acetoxy-3-acetoxymethyl-5,5,8-trioxo-5lambda*6*-...)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibitory concentration which is required to cause 50% inhibition of TrypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsin-like elastase family member 1/2A(Sus scrofa (Pig))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50015876(7-Acetoxy-3-acetoxymethyl-5,5,8-trioxo-5lambda*6*-...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibitory concentration which is required to cause 50% inhibition of porcine pancreatic elastase (PPE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50015876(7-Acetoxy-3-acetoxymethyl-5,5,8-trioxo-5lambda*6*-...)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibitory concentration which is required to cause 50% inhibition of bovine alpha-chymotrypsin (ChT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50015876(7-Acetoxy-3-acetoxymethyl-5,5,8-trioxo-5lambda*6*-...)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibitory concentration which is required to cause 50% inhibition of human leukocyte elastase (HLE) enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed