BDBM50017715 CHEMBL125737::Tiapamil::[2-(3,4-Dimethoxy-phenyl)-ethyl]-{3-[2-(3,4-dimethoxy-phenyl)-1,1,3,3-tetraoxo-1lambda*6*,3lambda*6*-[1,3]dithian-2-yl]-propyl}-methyl-amine::[2-(3,4-dimethoxy-phenyl)-ethyl]-{3-[2-(3,4-dimethoxy-phenyl)-1,1,3,3-tetraoxo-1lambda6,3lambda6-[1,3]dithian-2-yl]-propyl}-methyl-amine

SMILES COc1ccc(CCN(C)CCCC2(c3ccc(OC)c(OC)c3)S(=O)(=O)CCCS2(=O)=O)cc1OC

InChI Key InChIKey=ZROUQTNYPCANTN-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50017715   

LigandPNGBDBM50017715(CHEMBL125737 | Tiapamil | [2-(3,4-Dimethoxy-phenyl...)
Affinity DataKi:  416nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50017715(CHEMBL125737 | Tiapamil | [2-(3,4-Dimethoxy-phenyl...)
Affinity DataKi:  1.44E+3nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50017715(CHEMBL125737 | Tiapamil | [2-(3,4-Dimethoxy-phenyl...)
Affinity DataIC50:  1.35E+4nMAssay Description:Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed