BDBM50019160 CHEMBL3289100

SMILES [H][C@]1([#6]-[#6][C@]2([#6])[#6]3=[#6]-[#6][C@@]4([H])C([#6])([#6])[#6@@H](-[#6]-[#6][C@]4([#6])[C@@]3([H])[#6]-[#6][C@@]12[#6])-[#8]-[#6](-[#6])=O)[#6@H](-[#6]-[#6]\[#6]=[#6](\[#6])-[#6])-[#6](-[#8])=O

InChI Key InChIKey=OCCMMQNWHUARRP-PFTIPHQLSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50019160   

TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
University Of Tuebingen

Curated by ChEMBL
LigandPNGBDBM50019160(CHEMBL3289100)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of ovine COX-1 using arachidonic acid as substrate preincubated for 5 mins followed by substrate addition measured after 5 mins by HPLC an...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
University Of Tuebingen

Curated by ChEMBL
LigandPNGBDBM50019160(CHEMBL3289100)
Affinity DataIC50:  400nMAssay Description:Inhibition of microsomal PGES1 isolated from IL-1beta-stimulated human A549 cells preincubated for 15 mins followed by substrate addition measured af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University Of Tuebingen

Curated by ChEMBL
LigandPNGBDBM50019160(CHEMBL3289100)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant COX-2 using arachidonic acid as substrate preincubated for 5 mins followed by substrate addition measured after 5 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed