BDBM50019162 CHEMBL3289103

SMILES [H][C@@]12[C@@H](C)[C@H](C)CC[C@]1(C)CC[C@]1(C)C2=CC(=O)[C@]2([H])[C@@](C)(CCC(O)=O)[C@@H](CC[C@@]12C)C(C)C

InChI Key InChIKey=KMCRGXMZSJGANR-SAOXLNNDSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50019162   

TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
University Of Tuebingen

Curated by ChEMBL
LigandPNGBDBM50019162(CHEMBL3289103)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of ovine COX-1 using arachidonic acid as substrate preincubated for 5 mins followed by substrate addition measured after 5 mins by HPLC an...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
University Of Tuebingen

Curated by ChEMBL
LigandPNGBDBM50019162(CHEMBL3289103)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of microsomal PGES1 isolated from IL-1beta-stimulated human A549 cells preincubated for 15 mins followed by substrate addition measured af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University Of Tuebingen

Curated by ChEMBL
LigandPNGBDBM50019162(CHEMBL3289103)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant COX-2 using arachidonic acid as substrate preincubated for 5 mins followed by substrate addition measured after 5 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed