BDBM50020717 CHEMBL3291433

SMILES Cc1[nH]c(c(c1-c1ccnc2[nH]c(=S)[nH]c(=O)c12)-c1ccccc1)-c1ccccc1

InChI Key InChIKey=RNAZYMHNUQJZSX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50020717   

TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Cairo University

Curated by ChEMBL
LigandPNGBDBM50020717(CHEMBL3291433)
Affinity DataIC50:  440nMAssay Description:Inhibition of GST-tagged HDM2 (unknown origin) expressed in Escherichia coli BL21 cells assessed as p53 activation by measuring inhibition of His-p53...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed