BDBM50021717 CHEMBL3298414

SMILES OC[C@@H](NC(=O)N1CCc2cnc(NC3CCOCC3)nc2C1)c1ccc(F)c(Cl)c1

InChI Key InChIKey=QTZUMCMRRPENJM-LJQANCHMSA-N

Data  1 KI  3 IC50

PDB links: 1 PDB ID matches this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50021717   

TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Array Biopharma

Curated by ChEMBL

LigandBDBM50021717(CHEMBL3298414)Copy SMILESCopy InChI

Affinity DataKi:  0.400nMAssay Description:Inhibition of 6-His tagged human ERK2 expressed in Escherichia coli measured over 30 mins by competition assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMedPDB3D Structure (crystal)
Copy BDB DOI