BDBM50022555 4-Hydroxy-2,8-bis-trifluoromethyl-quinoline-3-carboxylic acid thiazol-2-ylamide::CHEMBL33824

SMILES Oc1c(C(=O)Nc2nccs2)c(nc2c(cccc12)C(F)(F)F)C(F)(F)F

InChI Key InChIKey=ONLZCSMVKPIWON-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50022555   

TargetProstaglandin G/H synthase 1/2(Bos taurus)
Centre De Recherches Roussel-Uclaf

Curated by ChEMBL
LigandPNGBDBM50022555(4-Hydroxy-2,8-bis-trifluoromethyl-quinoline-3-carb...)
Affinity DataIC50:  400nMAssay Description:Inhibition of bovine Prostaglandin G/H synthase after oral administrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Centre De Recherches Roussel-Uclaf

Curated by ChEMBL
LigandPNGBDBM50022555(4-Hydroxy-2,8-bis-trifluoromethyl-quinoline-3-carb...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of 5-lipoxygenase from rat peritoneal neutrophils after oral administrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed