BDBM50022859 CHEMBL407670::Pro-His-Pro-Phe-His-Leu[CH2NH]Val-Ile-His-Lys::Pro-His-Prp-Phe-His-Leu(psi)[CH2NH]Val-Ile-His-Lys::Pro-His-Prp-Phe-His-Leu(psi)[CH2NH]Val-Ile-His-Lys(H-142)
SMILES CC[C@H](C)[C@H](NC(=O)[C@@H](NC[C@H](CC(C)C)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H]1CCCN1)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CCCCN)C(O)=O
InChI Key InChIKey=XIZSMQBWVQNHCA-NIRMQQKASA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50022859
Affinity DataIC50: 10nMAssay Description:Inhibition of Human plasma reninMore data for this Ligand-Target Pair
Affinity DataKd: 8nMAssay Description:Dissociation constant (Kd) of renin inhibitor was determined over a temperature range of 8-37 degree by the fluorescence displacement assayMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:In vitro inhibition of purified Human kidney renin (250 pg/mL) incubated with angiotensinogen at pH 7.2More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:In vitro inhibitory activity against human plasma reninMore data for this Ligand-Target Pair