BDBM50027176 2-Acetoxy-Benzoic Acid::3-Isobutyl-Methylxanthine::CHEBI:34795::ISOBUTYLMETHYLXANTHINE

SMILES CC(C)Cn1c2[nH]cnc2c(=O)n(C)c1=O

InChI Key InChIKey=APIXJSLKIYYUKG-UHFFFAOYSA-N

Data  3 KI  26 IC50

PDB links: 20 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50027176   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50027176(2-Acetoxy-Benzoic Acid | 3-Isobutyl-Methylxanthine...)
Affinity DataIC50:  2.82E+4nMAssay Description:Inhibition of human GST-tagged PDE4B expressed in baculovirus infected Sf9 insect cells using cAMP as substrate after 10 mins by PDE-Glo Phosphodiest...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Homo sapiens (Human))
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50027176(2-Acetoxy-Benzoic Acid | 3-Isobutyl-Methylxanthine...)
Affinity DataIC50:  8.56E+4nMAssay Description:Inhibition of human GST-tagged PDE7A expressed in baculovirus infected Sf9 insect cells using cAMP as substrate after 10 mins by PDE-Glo Phosphodiest...More data for this Ligand-Target Pair