BDBM50027661 CHEMBL3338417
SMILES ONC(=O)c1ccc2CC[C@@H](Cc2c1)Nc1nccc(n1)-c1cccnc1
InChI Key InChIKey=MWLFQRZKKHIDTM-KRWDZBQOSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50027661
TargetHistone deacetylase 6(Homo sapiens (Human))
Roche Pharmaceutical Research And Early Development
Curated by ChEMBL
Roche Pharmaceutical Research And Early Development
Curated by ChEMBL
Affinity DataEC50: 690nMAssay Description:Inhibition of HDAC6 in human A549 cells assessed as tubulin acetylation after 17 to 18 hrs by cytoblot assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 8(Homo sapiens (Human))
Roche Pharmaceutical Research And Early Development
Curated by ChEMBL
Roche Pharmaceutical Research And Early Development
Curated by ChEMBL
Affinity DataIC50: 390nMAssay Description:Inhibition of HDAC8 (unknown origin) using fluorogenic peptide as substrate by fluorescence assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Roche Pharmaceutical Research And Early Development
Curated by ChEMBL
Roche Pharmaceutical Research And Early Development
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of HDAC6 (unknown origin) using fluorogenic peptide as substrate by fluorescence assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
Roche Pharmaceutical Research And Early Development
Curated by ChEMBL
Roche Pharmaceutical Research And Early Development
Curated by ChEMBL
Affinity DataIC50: 1.12E+4nMAssay Description:Inhibition of HDAC1 (unknown origin) using fluorogenic peptide as substrate by fluorescence assayMore data for this Ligand-Target Pair