BDBM50028214 CHEMBL3354032

SMILES OC[C@H]1[C@@H](O)[C@H](O)[C@@H](O)CN1CCCCCOCC1C2CC3CC(C2)CC1C3

InChI Key InChIKey=BXIWEAVNUFIVND-JOJQPZRSSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50028214   

TargetNon-lysosomal glucosylceramidase(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50028214(CHEMBL3354032)
Affinity DataIC50:  2nMAssay Description:Inhibition of GBA2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50028214(CHEMBL3354032)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of GBA1 (unknown origin) using beta-D-[1-14C]glucocerebroside assessed as 4-methylumbelliferrone by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50028214(CHEMBL3354032)
Affinity DataIC50:  80nMAssay Description:Inhibition of glucosylceramide synthase (unknown origin) assessed as catabolism of NBD-glucosylceramideMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed